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TSH receptor antibody [2C11]

Cat No. GTX74844

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2C11

Isotype

 IgG1

Application

 WB, IHC-P, FACS, IP, ELISA

Reactivity

 Human
Package
100 μg ($329)
See all TSH receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 5-10μg/ml
IHC-P Assay dependent
FACS Assay dependent
IP 5-10μg/ml
ELISA Assay dependent
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

Specificity/Sensitivity

This antibody recognises both native and denatured TSH and no cross reactivity has been observed with related LH and FSH receptors.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human TSH receptor.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Thyroid Stimulating Hormone Receptor , Chng1 , Lgr3 , Htshr-I , Tshr

Background

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329