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TSH receptor antibody [2C11]

Cat No. GTX74844

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2C11

Isotype

 IgG1

Application

 WB, IHC-P, FACS, IP, ELISA

Reactivity

 Human
Package
100 μg ($339)
See all TSH receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 5-10μg/ml
IHC-P Assay dependent
FACS Assay dependent
IP 5-10μg/ml
ELISA Assay dependent
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

Product Note

This antibody recognises both native and denatured TSH and no cross reactivity has been observed with related LH and FSH receptors.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human TSH receptor.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_376500

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

thyroid stimulating hormone receptor , CHNG1 , LGR3 , hTSHR-I

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339