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TSH receptor antibody [49]

Anti-TSH receptor antibody [49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25492
Anti-TSH receptor antibody [49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25492
Anti-TSH receptor antibody [49] used in Western Blot (WB). GTX25492

Cat. No. GTX25492

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 49

Isotype

 IgG1

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Pig
Package
100 μl ($399)
See all TSH receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:250
ICC/IF 1:250
ELISA Assay dependent
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

Product Note

This antibody recognizes an epitope between amino acid residues 277-296 of human TSHR.

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified extracellular domain of recombinant human thyrotropin receptor.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

thyroid stimulating hormone receptor , CHNG1 , LGR3 , hTSHR-I

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Database

Research Area

DATA IMAGES

Anti-TSH receptor antibody [49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25492

GTX25492 ICC/IF Image

ICC/IF analysis of A431 cells using GTX25492 TSH receptor antibody [49]. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:200 overnight at 4ºC

Anti-TSH receptor antibody [49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25492

GTX25492 ICC/IF Image

ICC/IF analysis of A431 cells using GTX25492 TSH receptor antibody [49]. Panel e is a no primary antibody control.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : 4% paraformaldehyde
Permeabilization : 0.1% Triton X-100 for 10 minute
Dilution : 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature

Anti-TSH receptor antibody [49] used in Western Blot (WB). GTX25492

GTX25492 WB Image

WB analysis of membrane-enriched extracts (30 μg lysate) of A-431 (Lane 1), IMR-32 (Lane 2) and Jurkat (Lane 3) using GTX25492 TSH receptor antibody [49].
Dilution : 1:250

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399