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TSP antibody

Cat No. GTX73136

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IP

Reactivity

Human, Mouse, Bovine
Package
500 μl ($319)

APPLICATION

Application Note

Immunofluorescence; Immunoprecipitation (Native and denatured)(Using Protein A Ab. 10 micrograms/mg protein lysate); Western Blotting (Ab. 5-10 micrograms/ml 2 Hrs. RT)

Calculated MW

38 kDa. ( Note )

Positive Control

HUVEC Cells

PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.2, containing 0.2% BSA & 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human platelet TSP

Purification

Protein A affinity purified
From polyclonal serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Thrombopoietin , Mgdf , Mkcsf , Ml , Mpllg , Thcyt1 , Tpo , Thpo

Cellular Localization

Secrotory granules, golgi complex,ER, fibrillar extracellular matrix surrounding the cells.

Background

Thrombospondin represents about 25% of the protein content of platelet a-granules and is secreted at sites of platelet activation and aggregation suggesting that the protein has an important role in hemostasis. Given the involvement of TSP in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells, it is likely that TSP secreted at sites of wounding or clotting plays several important roles in this provisional matrix facilitating the healing process. The mature TSP peptide chain consists of 1152 amino acids and displays an apparent molecular weight of about 170 to 180kD on reducing SDS gels. The trimer of identical subunits of TSP is formed by interchain disulfides.

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 319