GeneTex
United States (US)

TTC8 antibody, Internal

GTX88117_2519_WB_18122102_363.jpg

Cat No. GTX88117

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-0.6μg/ml
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88117-PEP).

Specificity/Sensitivity

This antibody is expected to recognize all reported isoforms (NP_653197.2; NP_938051.1; NP_938052.1).

Predict Reactivity

Mouse, Bovine, Dog, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-KEVLKQDNTHVE, from the internal region of the protein sequence according to NP_653197.2; NP_938051.1; NP_938052.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

RP51 Antibody , BBS8 Antibody

Cellular Localization

Localizes to nonmembranous centriolar satellites in the cytoplasm.

Background

This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
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Database

Research Area

DATA IMAGES
GTX88117_2519_WB_18122102_363.jpg

GTX88117 WB Image

WB analysis of human testis lysate using GTX88117 TTC8 antibody, Internal.
Dilution : 0.2µg/ml
Loading : 35µg protein in RIPA buffer