GeneTex
United States (US)

TWEAK antibody

GTX16436_20180530_WB_18121410_907.jpg
GTX16436_20180530_IHC-P_18121410_959.jpg
GTX16436_20180530_IHC-P_3_18121410_313.jpg
GTX16436_20180530_IHC-P_2_18121410_316.jpg
GTX16436_20180530_IHC-P_1_18121410_207.jpg

Cat No. GTX16436

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

27 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 42-123 of human TNFSF12 (NP_003800.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tnf Superfamily Member 12,Apo3L,Dr3Lg,Tnlg4A,Tweak,Tnfsf12

Background

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

Database

Research Area

DATA IMAGES
GTX16436_20180530_WB_18121410_907.jpg

GTX16436 WB Image

WB analysis of various samples using GTX16436 TWEAK antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX16436_20180530_IHC-P_18121410_959.jpg

GTX16436 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX16436 TWEAK antibody.
Dilution : 1:100

GTX16436_20180530_IHC-P_3_18121410_313.jpg

GTX16436 IHC-P Image

IHC-P analysis of rat brain tissue using GTX16436 TWEAK antibody.
Dilution : 1:100

GTX16436_20180530_IHC-P_2_18121410_316.jpg

GTX16436 IHC-P Image

IHC-P analysis of mouse testis tissue using GTX16436 TWEAK antibody.
Dilution : 1:100

GTX16436_20180530_IHC-P_1_18121410_207.jpg

GTX16436 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX16436 TWEAK antibody.
Dilution : 1:100

Package List Price ($)
$ 319