APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:1000 |
| 1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide, corresponding to amino acids 51-100 of Human TWEAK.
Purification
Purified by antigen-affinity chromatography
From serum
Purity
> 95% (by SDS-PAGE)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
TNF superfamily member 12 , APO3L , DR3LG , TNLG4A , TWEAK
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
Database
Research Area
DATA IMAGES
|
GTX66870 WB Image
WB analysis of various samples using GTX66870 TWEAK antibody.
Lane1 : A549 whole cell lysate(40ug)
Lane2 : U-87MG whole cell lysate(40ug)
Lane3 : HEK293T whole cell lysate(40ug)
Lane4 : A2780 whole cell lysate(40ug)
Lane5 : SP2/0 whole cell lysate(40ug)
Lane6 : C6 whole cell lysate(40ug)
Lane7 : PC12 whole cell lysate(40ug)
Dilution : 1:500
|
|
|
GTX66870 IHC-P Image
IHC-P analysis of human colon carcinoma tissue using GTX66870 TWEAK antibody.
Left : Primary antibody
Right : Negative control
Dilution : 1:50
|
REFERENCE
There are currently no references for TWEAK antibody (GTX66870). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TWEAK antibody (GTX66870). Be the first to share your experience with this product.
