APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
*liver left adrenal vein tissue
Predict Reactivity
Human, Bovine, Pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris-Glycine (pH7), 10% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human TXA synthase. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_2038101
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
thromboxane A synthase 1 , BDPLT14 , CYP5 , CYP5A1 , GHOSAL , THAS , TS , TXAS , TXS
Cellular Localization
Membrane; Multi-pass membrane protein
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Database
Research Area
REFERENCE
There are currently no references for TXA synthase antibody [N3C3] (GTX102971). Be the first to share your publications with this product.
REVIEW
TXA synthase antibody [N3C3]
Cat No. GTX102971
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Rating
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( Average 3 based on 1 users reviews)
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Application
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Western Blot(WB)
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( Average 3 based on 1 users reviews)
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Date :
Anonymous submitted on 25-Dec-2014
Application Tested :
WB
Sample Species :
Rat
Sample :
left adrenal vein tissue
Amount used :
20μg
Blocking :
5% non-fat milk, 25°C, 1Hr
Primary Antibody :
1:1000, 4°C, 12Hr
![Anti-TXA synthase antibody [N3C3] used in Western Blot (WB). GTX102971](/upload/website/support/rewardsprogram/normal/genetex_GTX102971_WB-1_19080419_4ca4a909-c7b5-4d99-aafd-d1357e84ccec4126.jpg "Anti-TXA synthase antibody [N3C3] used in Western Blot (WB). GTX102971")