GeneTex
United States (US)

TXA synthase antibody [Tu-300]

Cat No. GTX15618

Host Mouse
Clonality Monoclonal
Clone Name Tu-300
Isotype IgG2a
Application IHC-Fr, IHC-F
Reactivity Human
APPLICATION

Application Note

IHC-Fr: 1/200. (Acetone fixation is recommended)Is unsuitable for WB. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

61 kDa. ( Note )

Specificity/Sensitivity

GTX15618 recognises native human TXA synthase.
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.01% Thimerosal (merthiolate). Constituents: PBS, 10mg/ml BSA. pH 7.2

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.4 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length native protein (purified human TXA synthase).

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Thromboxane A Synthase 1,Bdplt14,Cyp5,Cyp5A1,Ghosal,Thas,Ts,Txas,Txs,Tbxas1

Cellular Localization

Integral membrane protein.

Background

Anti Thromboxane Synthase is a useful marker for the detection of native thromboxane synthase in smears, isolated cells, human tissue sections, and for affinity purification of the enzyme. In combination with the markers 27E10, RM 3/1 and 25F9, anti Thromboxane Synthase enables a more precise characterization of inflammatory processes in injured tissues, or in vitro cell-cell interaction studies.Distribution of thromboxane synthase in human tissues: Thromboxane synthase is predominantly produced by macrophages or antigen presenting cells of the myelo-monocytic lineage as shown below. Endothelial cells of placenta and epithelial cells in tonsils and bronchi also express this enzyme.

Database

Research Area

Package List Price ($)
$ 329