APPLICATION
Application Note
IHC-Fr: 1/200. (Acetone fixation is recommended)Is unsuitable for WB. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
Product Note
GTX15618 recognises native human TXA synthase.
PROPERTIES
Form
Liquid
Buffer
PBS pH7.2, 10mg/ml BSA
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.4 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Full length native protein (purified human TXA synthase).
Purification
Protein G purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
thromboxane A synthase 1 , BDPLT14 , CYP5 , CYP5A1 , GHOSAL , THAS , TS , TXAS , TXS
Cellular Localization
Endoplasmic reticulum membrane
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Database
Research Area
REFERENCE
There are currently no references for TXA synthase antibody [Tu-300] (GTX15618). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TXA synthase antibody [Tu-300] (GTX15618). Be the first to share your experience with this product.