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TXA synthase antibody [Tu-300]

Cat. No. GTX15618

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Tu-300

Isotype

 IgG2a

Application

 IHC-Fr, IHC (Formalin)

Reactivity

 Human
Package
100 μg ($399)
See all TXA synthase products

APPLICATION

Application Note

IHC-Fr: 1/200. (Acetone fixation is recommended)Is unsuitable for WB. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

61 kDa. ( Note )

Product Note

GTX15618 recognises native human TXA synthase.

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 10mg/ml BSA

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.4 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length native protein (purified human TXA synthase).

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

thromboxane A synthase 1 , BDPLT14 , CYP5 , CYP5A1 , GHOSAL , THAS , TS , TXAS , TXS

Cellular Localization

Endoplasmic reticulum membrane

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Thimerosal.pdf
Package List Price ($)
$ 399