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TXNDC4 antibody [C1C3]

Anti-TXNDC4 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX106636
Anti-TXNDC4 antibody [C1C3] used in Western Blot (WB). GTX106636

Cat. No. GTX106636

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all TXNDC4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

293T , A431 , H1299

Predict Reactivity

Rat, Zebrafish, Bovine, Pig, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human TXNDC4. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1952458

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endoplasmic reticulum protein 44 , PDIA10 , TXNDC4

Cellular Localization

Endoplasmic reticulum lumen

Background

Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.

Database

Research Area

DATA IMAGES

Anti-TXNDC4 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX106636

GTX106636 IHC-P Image

Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using TXNDC4(GTX106636) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-TXNDC4 antibody [C1C3] used in Western Blot (WB). GTX106636

GTX106636 WB Image

Sample(30 ug whole cell lysate)
A:A431(GTX27909)
B:H1299
10% SDS PAGE
GTX106636 diluted at 1:1000

REFERENCE

Application Reference

Fu YL et al. Biochem Biophys Res Commun 2019; 511 (2) : 356-362 LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169