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TXNRD2 antibody [3F2-E12-F10]

Anti-TXNRD2 antibody [3F2-E12-F10] used in Western Blot (WB). GTX49270

Cat No. GTX49270

Host

Mouse

Clonality

Monoclonal

Clone Name

3F2-E12-F10

Isotype

IgG1

Application

WB

Reactivity

Human
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

ascites

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human TXNRD2 protein fragments expressed in E.coli.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Thioredoxin Reductase 2 , Gccd5 , Selz , Tr , Tr-Beta , Tr3 , Trxr2 , Txnrd2

Cellular Localization

Mitochondrion

Background

Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22.

Database

Research Area

DATA IMAGES

Anti-TXNRD2 antibody [3F2-E12-F10] used in Western Blot (WB). GTX49270

GTX49270 WB Image

WB analysis of A431, U251, U2OS, LNCAP and HeLa lysates using TXNRD2 antibody at a dilution of 1:1,000.

REFERENCE

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REVIEW

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