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United States (US)

Tafazzin / TAZ antibody [C2C3], C-term

Anti-Tafazzin / TAZ antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX106271

Cat No. GTX106271

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

Synthetic peptide: 1:8,000

Predict Reactivity

Chimpanzee(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Tafazzin / TAZ. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tafazzin,Bths,Cmd3A,Efe,Efe2,G4.5,Lvncx,Taz1,Taz

Cellular Localization

Isoform 1: Membrane; Single-pass membrane protein , Isoform 2: Cytoplasm , Isoform 3: Membrane; Single-pass membrane protein , Isoform 4: Membrane; Single-pass membrane protein , Isoform 5: Membrane; Single-pass membrane protein , Isoform 6: Cytoplasm , I

Background

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq]

Database

Research Area

DATA IMAGES
Anti-Tafazzin / TAZ antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX106271

GTX106271 IHC-P Image

TAZ antibody [C2C3], C-term detects TAZ protein at cytoplasm on human placenta by immunohistochemical analysis.
Sample: Paraffin-embedded placenta.
TAZ antibody [C2C3], C-term (GTX106271) dilution: 1:100.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169