GeneTex
United States (US)

Tapasin antibody

GTX16401_20180530_IHC-P_1_18121410_946.jpg
GTX16401_20180530_WB_18121410_214.jpg
GTX16401_20180530_IHC-P_18121410_517.jpg
GTX16401_20180530_IHC-P_4_18121410_160.jpg
GTX16401_20180530_IHC-P_3_18121410_804.jpg
GTX16401_20180530_IHC-P_2_18121410_584.jpg

Cat No. GTX16401

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

48 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-260 of human TAPBP (NP_757345.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tap Binding Protein,Ngs17,Tapa,Tpn,Tpsn,Tapbp

Background

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX16401_20180530_IHC-P_1_18121410_946.jpg

GTX16401 IHC-P Image

IHC-P analysis of human stomach tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

GTX16401_20180530_WB_18121410_214.jpg

GTX16401 WB Image

WB analysis of HT-29 cell lysate using GTX16401 Tapasin antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX16401_20180530_IHC-P_18121410_517.jpg

GTX16401 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

GTX16401_20180530_IHC-P_4_18121410_160.jpg

GTX16401 IHC-P Image

IHC-P analysis of rat testis tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

GTX16401_20180530_IHC-P_3_18121410_804.jpg

GTX16401 IHC-P Image

IHC-P analysis of mouse testis tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

GTX16401_20180530_IHC-P_2_18121410_584.jpg

GTX16401 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

Package List Price ($)
$ 319