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Tapasin antibody

Anti-Tapasin antibody used in IHC (Paraffin sections) (IHC-P). GTX16401
Anti-Tapasin antibody used in Western Blot (WB). GTX16401
Anti-Tapasin antibody used in IHC (Paraffin sections) (IHC-P). GTX16401
Anti-Tapasin antibody used in IHC (Paraffin sections) (IHC-P). GTX16401

Cat. No. GTX16401

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Tapasin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-260 of human TAPBP (NP_757345.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TAP binding protein , NGS17 , TAPA , TPN , TPSN

Cellular Localization

Endoplasmic reticulum membrane

Background

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Tapasin antibody used in IHC (Paraffin sections) (IHC-P). GTX16401

GTX16401 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

Anti-Tapasin antibody used in Western Blot (WB). GTX16401

GTX16401 WB Image

WB analysis of HT-29 cell lysate using GTX16401 Tapasin antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Tapasin antibody used in IHC (Paraffin sections) (IHC-P). GTX16401

GTX16401 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

Anti-Tapasin antibody used in IHC (Paraffin sections) (IHC-P). GTX16401

GTX16401 IHC-P Image

IHC-P analysis of rat testis tissue using GTX16401 Tapasin antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399