GeneTex
United States (US)

Tau (phospho Ser235) antibody

Tau-protein_18121411_886.jpg
GTX31113_1527_WB_18121410_860.jpg

Cat No. GTX31113

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

79 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.2, 0.05% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic phosphopeptide derived from human Tau around the phosphorylation site of Serine 235.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Microtubule Associated Protein Tau,Ddpac,Ftdp-17,Maptl,Mstd,Mtbt1,Mtbt2,Ppnd,Ppp1R103,Tau,Mapt

Cellular Localization

Cytoplasm,cytosol,Cell membrane, Peripheral membrane protein, Cytoplasmic side,cytoskeleton,Cell projection,axon

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]

Database

Research Area

DATA IMAGES
Tau-protein_18121411_886.jpg

GTX31113 Image

Tau protein schematic showing important functional domains and phosphorylation sites

GTX31113_1527_WB_18121410_860.jpg

GTX31113 WB Image

WB analysis of COLO205 cell lysate using GTX31113 Tau (phospho Ser235) antibody.

Package List Price ($)
$ 319