PBS pH 7.4, 0.02% sodium azide, 30% glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Batch dependent (Please refer to the vial label for the specific concentration.)
KLH-conjugated synthetic phospho-peptide mapping to residues surrounding Serine-400 of human Tau-F. A portion of this peptide contains the sequence PVVSGDT common to Tau isoforms (UniProt accession #P10636).
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
DDPAC , FTDP17 , MAPT , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU , microtubule associated protein tau , Tau , Neurofibrillary tangles , NFTs
Cytoplasm,Cytosol,Cell membrane,Cytoskeleton,Cell projection,Axon
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]