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TdT antibody [SEN28]

Anti-TdT antibody [SEN28] used in IHC (Paraffin sections) (IHC-P). GTX01873

Cat. No. GTX01873

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SEN28

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($709)
See all TdT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to the amino terminal region of the terminal deoxynucleotidyl transferase molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNA nucleotidylexotransferase , TDT

Cellular Localization

Nucleus

Background

This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TdT antibody [SEN28] used in IHC (Paraffin sections) (IHC-P). GTX01873

GTX01873 IHC-P Image

IHC-P analysis of human thymus tissue using GTX01873 TdT antibody [SEN28]. Note nuclear staining for cortical thymic lymphocytes.

REFERENCE

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REVIEW

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Package List Price ($)
$ 709