*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Rat, Bovine, Dog, Pig, Rhesus Monkey(>80% identity)
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Full length human Telethonin Recombinant protein.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
titin-cap , CMD1N , CMH25 , LGMD2G , LGMDR7 , T-cap , TELE , telethonin
Cytoplasm , myofibril , sarcomere
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]
GTX109265 IHC-P Image
Telethonin antibody [N1C3] detects Telethonin protein at cytoplasm in Huh7 xenograft by immunohistochemical analysis.
Sample: Paraffin-embedded Huh7 xenograft.
Telethonin antibody [N1C3] (GTX109265) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX109265 WB Image
Telethonin antibody detects Telethonin protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with Telethonin antibody (GTX109265) diluted at 1:500.