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Thrombomodulin antibody [THBD/1591]

Anti-Thrombomodulin antibody [THBD/1591] used in Western Blot (WB). GTX35108
Anti-Thrombomodulin antibody [THBD/1591] used in IHC (Paraffin sections) (IHC-P). GTX35108
Anti-Thrombomodulin antibody [THBD/1591] used in IHC (Paraffin sections) (IHC-P). GTX35108
Anti-Thrombomodulin antibody [THBD/1591] used in Protein Array (Protein Array). GTX35108
Anti-Thrombomodulin antibody [THBD/1591] used in IHC (Paraffin sections) (IHC-P). GTX35108

Cat. No. GTX35108

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 THBD/1591

Isotype

 IgG2b

Application

 WB, IHC-P, ELISA, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all Thrombomodulin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
ELISA 2-4μg/ml (for coating)
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AHUS6 , BDCA3 , CD141 , THBD , THPH12 , THRM , TM , thrombomodulin

Cellular Localization

Membrane

Background

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Thrombomodulin antibody [THBD/1591] used in Western Blot (WB). GTX35108

GTX35108 WB Image

WB analysis of (A) recombinant Thrombomodulin protein (B) THP1 cell lysates using GTX35108 Thrombomodulin antibody [THBD/1591].

Anti-Thrombomodulin antibody [THBD/1591] used in IHC (Paraffin sections) (IHC-P). GTX35108

GTX35108 IHC-P Image

IHC-P analysis of human placenta tissue using GTX35108 Thrombomodulin antibody [THBD/1591].

Anti-Thrombomodulin antibody [THBD/1591] used in IHC (Paraffin sections) (IHC-P). GTX35108

GTX35108 IHC-P Image

IHC-P analysis of human cervical carcinoma tissue using GTX35108 Thrombomodulin antibody [THBD/1591].

Anti-Thrombomodulin antibody [THBD/1591] used in Protein Array (Protein Array). GTX35108

GTX35108 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using Thrombomodulin/CD141 Mouse Monoclonal Antibody (THBD/1591). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-Thrombomodulin antibody [THBD/1591] used in IHC (Paraffin sections) (IHC-P). GTX35108

GTX35108 IHC-P Image

IHC-P analysis of human bladder carcinoma tissue using GTX35108 Thrombomodulin antibody [THBD/1591].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529