GeneTex

  • Country / Location Selection

United States (US)

Thymidine Phosphorylase antibody [P-GF.44C]

Cat. No. GTX23151

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 P-GF.44C

Isotype

 IgG1

Application

 WB, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
500 μl ($319)
See all Thymidine Phosphorylase products

APPLICATION

Application Note

Western Blotting: assay dependent. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 1 - 2μg / ml for 30 min at RT. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 55 kDa, which corresponds to the predicted molecular weight of Thymidine Phosphorylase. No special pretreatment is required for immuno-histochemical staining of formalin-fixed tissues

Calculated MW

50 kDa. ( Note )

Positive Control

HUVEC cells. Breast carcinoma.

PROPERTIES

Form

Liquid

Buffer

10mM PBS pH7.4, Gelatin

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length human thymidine phosphorylase (TP / PD-ECGF) protein.

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_384959

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

thymidine phosphorylase , ECGF , ECGF1 , MEDPS1 , MNGIE , MTDPS1 , PDECGF , TP , hPD-ECGF

Background

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

Database

Research Area

REFERENCE

Application Reference

J?r?mie Gautheron et al. BMC Med 2022; 20 (1) : 95 Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
Application : WB
Gajjar KK et al. Int J Biol Markers 2018; 33 (2) : 180-188 deciphering the potential value of 5-* metabolic enzymes in predicting prognosis and treatment response of colorectal cancer patients.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for Thymidine Phosphorylase antibody [P-GF.44C] (GTX23151). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319