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Thymidine Phosphorylase antibody [P-GF.44C]

Cat No. GTX23151

Host

Mouse

Clonality

Monoclonal

Clone Name

P-GF.44C

Isotype

IgG1

Application

WB, IHC-P, IHC-Fr

Reactivity

Human, Mouse, Rat
Package
500 μl ($319)

APPLICATION

Application Note

Western Blotting: assay dependent. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 1 - 2μg / ml for 30 min at RT. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 55 kDa, which corresponds to the predicted molecular weight of Thymidine Phosphorylase. No special pretreatment is required for immuno-histochemical staining of formalin-fixed tissues

Calculated MW

50 kDa. ( Note )

Positive Control

HUVEC cells. Breast carcinoma.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, pH7.4 containing gelatin and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length human thymidine phosphorylase (TP / PD-ECGF) protein.

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_384959

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

thymidine phosphorylase , ECGF , ECGF1 , MEDPS1 , MNGIE , MTDPS1 , PDECGF , TP , hPD-ECGF

Background

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

Database

Research Area

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf