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Thymidine Phosphorylase antibody [P-GF.44C]

Anti-Thymidine Phosphorylase antibody [P-GF.44C] used in IHC (Paraffin sections) (IHC-P). GTX35111

Cat. No. GTX35111

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 P-GF.44C

Isotype

 IgG1

Application

 WB, IHC-P, IP

Reactivity

 Human, Mouse, Rat
Package
100 μg ($529)
See all Thymidine Phosphorylase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
IP 0.5-1μg/500ug protein lysate

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human Thymidine Phosphorylase (TP / PD-ECGF) protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ECGF , ECGF1 , MEDPS1 , MNGIE , MTDPS1 , PDECGF , TP , TYMP , hPDECGF , thymidine phosphorylase , PD-ECGF , Thymidine Phosphorylase

Background

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

Database

Research Area

DATA IMAGES

Anti-Thymidine Phosphorylase antibody [P-GF.44C] used in IHC (Paraffin sections) (IHC-P). GTX35111

GTX35111 IHC-P Image

IHC-P analysis of human placenta tissue using GTX35111 Thymidine Phosphorylase antibody [P-GF.44C].

REFERENCE

Clone Reference

J?r?mie Gautheron et al. BMC Med 2022; 20 (1):95 Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
Gajjar KK et al. Int J Biol Markers 2018; 33 (2):180-188 deciphering the potential value of 5-* metabolic enzymes in predicting prognosis and treatment response of colorectal cancer patients.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529