GeneTex
  • Country / Location Selection

United States (US)

Thyroglobulin antibody [2H11 + 6E1]

Cat No. GTX01838

Host

Mouse

Clonality

Monoclonal

Clone Name

2H11 + 6E1

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human, Rat
Package
500 μl ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 1:100-1:200

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.

Not tested in other applications.

Calculated MW

305 kDa. ( Note )

Positive Control

Thyroid

Product Note

Clone [2H11 + 6E1] cocktail is especially designed for sensitive detection of thyroglobulin. It stains thyroglobulin in follicular epithelial cells as well as colloid tissue.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant diluted in Tris-HCl buffer, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human thyroglobulin

Purification

unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

thyroglobulin , AITD3 , TGN

Cellular Localization

Secreted

Background

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]

Database

Research Area

REFERENCE

REVIEW

There are currently no reviews for Thyroglobulin antibody [2H11 + 6E1] (GTX01838). Be the first to share your experience with this product.
Package List Price ($)
$ 379