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Thyroglobulin antibody [MSVA-189R] HistoMAX™

HistoMAX
Anti-Thyroglobulin antibody [MSVA-189R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04365
Anti-Thyroglobulin antibody [MSVA-189R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04365
Anti-Thyroglobulin antibody [MSVA-189R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04365

Cat. No. GTX04365

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-189R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($629),
100 μl ($299)
See all Thyroglobulin products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 6.0 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

305 kDa. ( Note )

Positive Control

Thyroid: A strong staining is seen in follicular cells and the colloid. The stroma is typically also stained due to a contamination artifact.

Negative Control

Colon: All cells must not show any staining.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human Thyroglobulin protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

thyroglobulin , AITD3 , TGN

Cellular Localization

Secreted

Background

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES

Anti-Thyroglobulin antibody [MSVA-189R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04365

GTX04365 IHC-P Image

IHC-P analysis of human rectum mucosa tissue section using GTX04365 Thyroglobulin antibody [MSVA-189R] HistoMAX™.

Anti-Thyroglobulin antibody [MSVA-189R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04365

GTX04365 IHC-P Image

IHC-P analysis of human follicular thyroid cancer tissue section using GTX04365 Thyroglobulin antibody [MSVA-189R] HistoMAX™.
Follicular thyroid cancer with strong thyroglobulin expression.

Anti-Thyroglobulin antibody [MSVA-189R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04365

GTX04365 IHC-P Image

IHC-P analysis of human thyroid gland tissue section using GTX04365 Thyroglobulin antibody [MSVA-189R] HistoMAX™.

REFERENCE

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REVIEW

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Package List Price ($)
$ 629
$ 299