Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1,000 |
1:20 |
1:20 |
Assay dependent |
Assay dependent |
Not tested in other applications.
Product Note
This antibody recognizes TR beta-1 and also cross-reacts with TR alpha-1. This antibody recognizes an epitope in the hormone binding domain of hTR beta-1, amino acid residues 235-414.
Form
Liquid
Buffer
Ascites
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified fragment of human TR beta-1 corresponding to residues 201-456.
Purification
Unpurified
Conjugation
Unconjugated
RRID
AB_374338
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Synonyms
thyroid hormone receptor alpha , thyroid hormone receptor beta , AR7 , CHNG6 , EAR7 , ERB-T-1 , ERBA , ERBA1 , NR1A1 , THRA1 , THRA2 , c-ERBA-1 , C-ERBA-2 , C-ERBA-BETA , ERBA2 , GRTH , NR1A2 , PRTH , THR1 , THRB1 , THRB2
Cellular Localization
Nucleus
Background
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Database
Research Area