GeneTex
  • Country / Location Selection

United States (US)

Thyroid Hormone Receptor beta antibody, Internal

Anti-Thyroid Hormone Receptor beta antibody, Internal used in Western Blot (WB). GTX88979

Cat No. GTX88979

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-1μg/ml
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88979-PEP).

Product Note

This antibody is not expected to cross-react to THRA.

Predict Reactivity

Mouse, Rat, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS pH7.3, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-REELQKSIGHKP, from the internal region of the protein sequence according to NP_000452.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

thyroid hormone receptor beta , C-ERBA-2 , C-ERBA-BETA , ERBA2 , GRTH , NR1A2 , PRTH , THR1 , THRB1 , THRB2

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Thyroid Hormone Receptor beta antibody, Internal used in Western Blot (WB). GTX88979

GTX88979 WB Image

WB analysis of human bone marrow lysate using GTX88979 Thyroid Hormone Receptor beta antibody, Internal.
Dilution : 0.3μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

There are currently no references for Thyroid Hormone Receptor beta antibody, Internal (GTX88979). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Thyroid Hormone Receptor beta antibody, Internal (GTX88979). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 369