*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Thyroid Hormone Receptor beta (cleaved Arg327) antibody detects endogenous levels of fragment of activated THRB resulting from cleavage adjacent to Arg327.
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
0.02% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Batch dependent (Please refer to the vial label for the specific concentration.)
The antiserum was produced against synthesized peptide derived from human Thyroid Hormone Receptor beta (278-327).
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CERBA2 , CERBABETA , ERBA2 , GRTH , NR1A2 , PRTH , THR1 , THRB , THRB1 , THRB2 , thyroid hormone receptor beta , Thyroid Hormone Receptor beta , thyroid hormone receptor, beta
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
GTX86914 WB Image
WB analysis of Jurkat cells treated with etoposide 25uM 24H using GTX86914 Thyroid Hormone Receptor beta (cleaved Arg327) antibody.