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Tollip antibody [Kimmy-2]

Cat. No. GTX16089

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Kimmy-2

Isotype

 IgG1

Application

 WB, IP

Reactivity

 Human, Mouse
Package
50 μg ($399)
See all Tollip products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IP Assay dependent
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Tollip (monoclonal Kimmy-2) antibody was raised against recombinant mouse Tollip (aa. 1-274).

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll interacting protein , 4930403G24Rik , 4931428G15Rik

Cellular Localization

Cytoplasm

Background

Toll like protein is a component of the signaling pathway of IL-1 and Toll-like receptors. It inhibits cell activation by microbial products. Tollip recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. It oligomerizes and binds to TLR2 and the TLR4-MD2 complex via its C-terminus.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399