GeneTex
United States (US)

Tollip antibody [Kimmy-2]

Cat No. GTX16089

Host Mouse
Clonality Monoclonal
Clone Name Kimmy-2
Isotype IgG1
Application WB, IP
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IP Assay dependent
Not tested in other applications.

Calculated MW

30 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Tollip (monoclonal Kimmy-2) antibody was raised against recombinant mouse Tollip (aa. 1-274).

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Toll Interacting Protein,4930403G24Rik,4931428G15Rik,Tollip

Cellular Localization

Cytoplasmic

Background

Toll like protein is a component of the signaling pathway of IL-1 and Toll-like receptors. It inhibits cell activation by microbial products. Tollip recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. It oligomerizes and binds to TLR2 and the TLR4-MD2 complex via its C-terminus.

Database

Research Area

Package List Price ($)
$ 319