GeneTex
United States (US)

Transferrin antibody [2A2]

Cat No. GTX10211

Host Mouse
Clonality Monoclonal
Clone Name 2A2
Isotype IgG1
Application ICC/IF, ELISA
Reactivity Human
APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. FuncS: Use at an assay dependent dilution. Inhibits the proliferation of con A stimulated peripheral blodd lymphocytes at 10^-6M. IF: Use at an assay dependent dilution. Works in indirect immunofluorescence on fixed paraffin embedded human brain tissue. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

77 kDa. ( Note )

Specificity/Sensitivity

Reacts with the N-terminal domain of human transferrin (Kd 2.85 X 10-11). Does not cross react with mouse rabbit or bovine transferrin or with human lactoferrin.
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

2mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified transferrin from pooled human plasma

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PRO1557, TF, PRO2086, 7018, P02787, Transferrin, 190000

Cellular Localization

Secreted

Background

The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Database

Research Area