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Transgelin antibody

Anti-Transgelin antibody used in Western Blot (WB). GTX04761
Anti-Transgelin antibody used in IHC (Paraffin sections) (IHC-P). GTX04761
Anti-Transgelin antibody used in Flow cytometry (FACS). GTX04761
Anti-Transgelin antibody used in Western Blot (WB). GTX04761

Cat. No. GTX04761

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, FACS

Reactivity

Human
Package
400 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human TAGLN.

Purification

Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SM22,SMCC,TAGLN,TAGLN1,WS310,transgelin,Transgelin,SM22 alpha,Tagln

Cellular Localization

Cytoplasm

Background

This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Transgelin antibody used in Western Blot (WB). GTX04761

GTX04761 WB Image

WB analysis of SK-Br-3 whole cell lysate using GTX04761 Transgelin antibody.
Loading : 35 μg

Anti-Transgelin antibody used in IHC (Paraffin sections) (IHC-P). GTX04761

GTX04761 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX04761 Transgelin antibody.

Anti-Transgelin antibody used in Flow cytometry (FACS). GTX04761

GTX04761 FACS Image

FACS analysis of MDA-MB468 cells using GTX04761 Transgelin antibody.
Top panel : Negative control
Bottom panel : Primary antibody

Anti-Transgelin antibody used in Western Blot (WB). GTX04761

GTX04761 WB Image

WB analysis of human uterus tissue lysate using GTX04761 Transgelin antibody.
Loading : 20 μg
Dilution : 1:8000

REFERENCE

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REVIEW

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Package List Price ($)
$ 399