GeneTex
United States (US)

Translin antibody

Anti-Translin antibody used in IHC (Paraffin sections) (IHC-P). GTX31440
Anti-Translin antibody used in Western Blot (WB). GTX31440
Anti-Translin antibody used in IHC (Paraffin sections) (IHC-P). GTX31440

Cat No. GTX31440

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Positive Control

Rat Lung Tissue Lysate(GTX27941) , Human Lung Tissue Slide

Specificity/Sensitivity

At least two isoforms of Translin are known to exist; this antibody will detect both.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin.The immunogen is located within the last 50 amino acids of Translin.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Translin,Bclf-1,C3Po,Rchf1,Rehf-1,Tbrbp,Trsln,Tsn

Background

This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Database

DATA IMAGES
Anti-Translin antibody used in IHC (Paraffin sections) (IHC-P). GTX31440

GTX31440 IHC-P Image

IHC-P analysis of human lung tissue using GTX31440 Translin antibody.
Working concentration : 5 μg/ml

Anti-Translin antibody used in Western Blot (WB). GTX31440

GTX31440 WB Image

WB analysis of rat lung tissue lysate using GTX31440 Translin antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-Translin antibody used in IHC (Paraffin sections) (IHC-P). GTX31440

GTX31440 IHC-P Image

IHC-P analysis of human lung tissue using GTX31440 Translin antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 339