GeneTex
United States (US)

Trek1 antibody

GTX16653_WB_18121410_253.jpg

Cat No. GTX16653

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

We recommend the following starting dilutions: For WB: Use at a dilution of 1:200. For ICC/IF: Use at a dilution of 1:100. Optimal dilutions should be determined experimentally by the end user.

Calculated MW

47 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide DPKSAAQNSKPRLSFSTK(C), corresponding to residues 8-25 of human K2P2.1 (TREK-1) (Accession O95069). Intracellular, N-terminus.

Purification

Affinity purified on immobilized antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Potassium Two Pore Domain Channel Subfamily K Member 2,K2P2.1,Tpkc1,Trek,Trek-1,Trek1,Htrek-1C,Htrek-1E,Kcnk2

Background

This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16653_WB_18121410_253.jpg

GTX16653 WB Image

Western blot analysis of rat brain membranes lysates using Trek1 antibody. Lane 1: Anti-TREK-1 antibody, (1:200). Lane 2: Anti-TREK-1 antibody, preincubated with the control peptide antigen.

Package List Price ($)
$ 329