Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Peptide DPKSAAQNSKPRLSFSTK(C), corresponding to residues 8-25 of human K2P2.1 (TREK-1) (Accession O95069). Intracellular, N-terminus.
Affinity purified on immobilized antigen.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Potassium Two Pore Domain Channel Subfamily K Member 2,K2P2.1,Tpkc1,Trek,Trek-1,Trek1,Htrek-1C,Htrek-1E,Kcnk2
This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]