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Trk antibody (ready-to-use)

Anti-Trk antibody (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX05015

Cat. No. GTX05015

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
6 ml ($419)
See all Trk products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:200

Note :

IHC-P
Recommendations for antigen retrieval : EDTA buffer pH 8.0
Not tested in other applications.

Positive Control

Human cerebral cortex tissue

PROPERTIES

Form

Liquid

Buffer

Batch dependent

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide-KLH conjugate with human Trk A (777-796aa)

Purification

Purified IgG
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MTC,NTRK1,TRK,TRK1,TRKA,TrkA,neurotrophic receptor tyrosine kinase1,p140TrkA

Cellular Localization

Cell membrane,Early endosome membrane,Late endosome membrane

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Trk antibody (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX05015

GTX05015 IHC-P Image

IHC-P analysis of human celebellum tissue using GTX05015 Trk antibody (ready-to-use).

REFERENCE

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REVIEW

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Package List Price ($)
$ 419