GeneTex
  • Country / Location Selection

United States (US)

TrkA antibody [8X5]

Cat No. GTX53040

Host

Mouse

Clonality

Monoclonal

Clone Name

8X5

Isotype

IgG2

Application

WB

Reactivity

Human
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant Trk-A

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

MTC , NTRK1 , TRK , TRK1 , TRKA , TrkA , neurotrophic receptor tyrosine kinase 1 , p140TrkA , neurotrophic tyrosine kinase, receptor, type 1

Cellular Localization

Cell membrane,Early endosome membrane,Late endosome membrane

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for TrkA antibody [8X5] (GTX53040). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TrkA antibody [8X5] (GTX53040). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 359