TrkA antibody [EPR1104(2)]

Cat No. GTX62801

Host	Rabbit
Clonality	Monoclonal
Clone Name	EPR1104(2)
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse, Rat
Package	100 μl ($339)

See all TrkA products

Datasheet
Document

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:1000-1:10000
IHC-P	1:250-1:500

Not tested in other applications.

Calculated MW

87 kDa. ( Note )

Product Note

GTX62801 is specific for Human TrkA.

PROPERTIES

Form

Liquid

Buffer

50mM Tris-Glycine (pH7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to residues in human TrkA was used as an immunogen.

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,488.

TARGET

Synonyms

neurotrophic receptor tyrosine kinase 1 , MTC , TRK , TRK1 , TRKA , Trk-A , p140-TrkA

Cellular Localization

Cell membrane

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]

Database

Gene ID: 4914 NTRK1
UniProt: P04629 NTRK1

Research Area

DATA IMAGES

GTX62801 IHC-P Image

IHC analysis of normal liver tissue with TrkA antibody [EPR1104(2)] shows a negative staining.

GTX62801 IHC-P Image

IHC analysis of normal kidney tissue with TrkA antibody [EPR1104(2)] shows a negative staining.

GTX62801 IHC-P Image

IHC analysis of normal tonsil tissue with TrkA antibody [EPR1104(2)] shows a negative staining.

GTX62801 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-Trk A rabbit mAb (cat. #GTX62801).

GTX62801 IHC-P Image

IHC analysis of normal colon tissue with TrkA antibody [EPR1104(2)] shows a negative staining.

GTX62801 WB Image

Western blot analysis on (A) fetal brain and (B) SH-SY5Y lysates using anti-Trk A rabbit mAb (cat. #GTX62801).

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 339

Qty

TrkA antibody [EPR1104(2)]

Cat No. GTX62801

Host

Clonality

Clone Name

Isotype

Application

Reactivity

APPLICATION

Application Note

Calculated MW

Product Note

PROPERTIES

Form

Buffer

Preservative

Storage

Antigen Species

Immunogen

Purification

Conjugation

Note

TARGET

Synonyms

Cellular Localization

Background

Database

Research Area

DATA IMAGES

GTX62801 IHC-P Image

GTX62801 IHC-P Image

GTX62801 IHC-P Image

GTX62801 IHC-P Image

GTX62801 IHC-P Image

GTX62801 WB Image

REFERENCE

REVIEW

Product

Research

Support

Company

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All products are for research use only—Not for use in diagnostic or therapeutic applications.