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TrkA antibody

Anti-TrkA antibody used in Flow cytometry (FACS). GTX81329
Anti-TrkA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX81329
Anti-TrkA antibody used in Western Blot (WB). GTX81329

Cat. No. GTX81329

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, FACS

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all TrkA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This TrkA antibody is generated from rabbits immunized with TrkA his fusion protein

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neurotrophic receptor tyrosine kinase 1 , MTC , TRK , TRK1 , TRKA , Trk-A , p140-TrkA

Cellular Localization

Cell membrane

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TrkA antibody used in Flow cytometry (FACS). GTX81329

GTX81329 FACS Image

FACS analysis of WiDr cells using GTX81329 TrkA antibody.
Green : primary antibody
Blue : negative control

Anti-TrkA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX81329

GTX81329 ICC/IF Image

ICC/IF analysis of MDA-MB231 cells using GTX81329 TrkA antibody.
Green : TrkA
Blue : DAPI

Anti-TrkA antibody used in Western Blot (WB). GTX81329

GTX81329 WB Image

WB analysis of mouse brain tissue lysate (35ug/lane) using GTX81329 TrkA antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399