APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Dilution |
1:500 - 1:1000 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Human, Rat(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human TrkB around the phosphorylation site of tyrosine 705 (T-D-Y P-Y-R).
Purification
Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum
Conjugation
Unconjugated
RRID
AB_11169195
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
GP145TrkB,NTRK2,TRKB,neurotrophic receptor tyrosine kinase 2,trkB,TrkB,Trk B
Cellular Localization
Cell membrane,Endosome membrane,Early endosome membrane
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Database
Research Area
DATA IMAGES
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GTX78928 WB Image
WB analysis of mouse brain tissue lysate using GTX78928 TrkB (phospho Tyr705) antibody.
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REFERENCE
There are currently no references for TrkB (phospho Tyr705) antibody (GTX78928). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TrkB (phospho Tyr705) antibody (GTX78928). Be the first to share your experience with this product.