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TrkC antibody [4G5]

Anti-TrkC antibody [4G5] used in Western Blot (WB). GTX83316
Anti-TrkC antibody [4G5] used in Western Blot (WB). GTX83316

Cat. No. GTX83316

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4G5

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human, Rat
Package
100 μl ($399)
See all TrkC products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ELISA 1/10000
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant extracellular fragment of human TrkC (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neurotrophic receptor tyrosine kinase 3 , GP145-TrkC , TRKC , gp145(trkC)

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Database

Research Area

DATA IMAGES

Anti-TrkC antibody [4G5] used in Western Blot (WB). GTX83316

GTX83316 WB Image

WB analysis of extracellular domain of human NTRK3 (aa32-429) using GTX83316 TrkC antibody [4G5].

Anti-TrkC antibody [4G5] used in Western Blot (WB). GTX83316

GTX83316 WB Image

The data was published in the 2021 in Stem Cell Res Ther. PMID: 34020702

REFERENCE

Application Reference

Yi Cui et al. Stem Cell Res Ther 2021; 12 (1) : 298 The Rotary Cell Culture System increases NTRK3 expression and promotes neuronal differentiation and migratory ability of neural stem cells cultured on collagen sponge.
Application : WB
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399