APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1/500 - 1/2000 |
1/200 - 1/1000 |
1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant extracellular fragment of human TrkC (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
neurotrophic receptor tyrosine kinase 3 , GP145-TrkC , TRKC , gp145(trkC)
Cellular Localization
Membrane; Single-pass type I membrane protein
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Database
Research Area
DATA IMAGES
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GTX83321 IHC-P Image
IHC-P analysis of human lymph node using GTX83321 TrkC antibody [7H6].
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GTX83321 WB Image
WB analysis of extracellular domain of human NTRK3 (aa32-429) using GTX83321 TrkC antibody [7H6].
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REFERENCE
There are currently no references for TrkC antibody [7H6] (GTX83321). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TrkC antibody [7H6] (GTX83321). Be the first to share your experience with this product.