GeneTex
United States (US)

TrkC antibody [N2C1], Internal

GTX102525_WB_19011506_988.jpg
GTX102525_WB_M_19011506_921.jpg

Cat No. GTX102525

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

Positive Control

293T , A431 , H1299 , HeLaS3 , Molt-4 , Raji , NIH-3T3

Predict Reactivity

Rat, Bovine, Chicken, Pig, Chimpanzee, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human TrkC. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Neurotrophic Receptor Tyrosine Kinase 3,Gp145-Trkc,Trkc,Gp145(Trkc),Ntrk3

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX102525_WB_19011506_988.jpg

GTX102525 WB Image

Sample(30 ug whole cell lysate)
A:MOLT4 (GTX27912)
7.5% SDS PAGE
GTX102525 diluted at 1:1000

GTX102525_WB_M_19011506_921.jpg

GTX102525 WB Image

Sample (30 ug of whole cell lysate)

A:NIH-3T3
7.5% SDS PAGE

GTX102525 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf