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TrkC antibody

Overexpression
Anti-TrkC antibody used in Live cell imaging (LCI). GTX54858
Anti-TrkC antibody used in IHC (Frozen sections) (IHC-Fr). GTX54858
Anti-TrkC antibody used in Western Blot (WB). GTX54858
Anti-TrkC antibody used in Western Blot (WB). GTX54858
Anti-TrkC antibody used in IHC (Paraffin sections) (IHC-P). GTX54858

Cat. No. GTX54858

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, LCI

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all TrkC products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
LCI Assay dependent
Not tested in other applications.

Calculated MW

97 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)GHFLKEPFPESTD, corresponding to amino acid residues 393-405 (Extracellular, N-terminus) of rat TrkC (Accession  : Q03351).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887897

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neurotrophic receptor tyrosine kinase 3 , trkC

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

a tyrosine-protein kinase receptor for neurotrophin-3 [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-TrkC antibody used in Live cell imaging (LCI). GTX54858

GTX54858 LCI Image

Live cell imaging analysis of live intact PC12 cells using GTX54858 TrkC antibody.
Panel A : Primary antibody (Red)
Panel B : Hoechst 33342 for nuclear staining (blue)
Panel C : Merged images of Panel A and B
Dilution : 1:50

Anti-TrkC antibody used in IHC (Frozen sections) (IHC-Fr). GTX54858

GTX54858 IHC-Fr Image

IHC-Fr analysis of rat dorsal root ganglia tissue using GTX54858 TrkC antibody.
Panel A : TrkC (red) appears in cell bodies. Note that the nerve fibers are not stained.
Panel B : Nuclear staining (blue) was visualized using Hoechst 33342.
Panel C : Merge of A and B.
Dilution : 1:100

Anti-TrkC antibody used in Western Blot (WB). GTX54858

GTX54858 WB Image

Overexpression

WB analysis of HEK-TrkC transfected cells (lanes 1 and 3) and HEK untransfected cells (lanes 2 and 4) lysates using GTX54858 TrkC antibody preincubated with or without immunogen peptide.
Dilution : 1:400

Anti-TrkC antibody used in Western Blot (WB). GTX54858

GTX54858 WB Image

The data was published in the journal J Cancer in 2019. PMID: 31762816

Anti-TrkC antibody used in IHC (Paraffin sections) (IHC-P). GTX54858

GTX54858 IHC-P Image

The data was published in the journal J Cancer in 2019. PMID: 31762816

REFERENCE

Application Reference

Li H et al. J Cancer 2019; 10 (24) : 6065-6073 NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma.
Application : WB
Reactivity : Human
Huan Li et al. Journal of Cancer 2019; 10 (24) : 6065-6073 NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma.
Application : WB, IHC-P
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639