GeneTex

  • Country / Location Selection

United States (US)

Tropomyosin 3 antibody

Anti-Tropomyosin 3 antibody used in Western Blot (WB). GTX16386
Anti-Tropomyosin 3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16386

Cat. No. GTX16386

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Tropomyosin 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-284 of human TPM3 (NP_689476.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tropomyosin 3 , CAPM1 , CFTD , HEL-189 , HEL-S-82p , NEM1 , OK/SW-cl.5 , TM-5 , TM3 , TM30 , TM30nm , TM5 , TPM3nu , TPMsk3 , TRK , hscp30

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-Tropomyosin 3 antibody used in Western Blot (WB). GTX16386

GTX16386 WB Image

WB analysis of various sample lysates using GTX16386 Tropomyosin 3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Tropomyosin 3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16386

GTX16386 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX16386 Tropomyosin 3 antibody.
Blue : DAPI

REFERENCE

Application Reference

Akihiro T et al. Sci Rep 2022; 12 (1) : 15253 Tropomyosin micelles are the major components contributing to the white colour of boiled shellfish soups.
Application : WB
Submit a Reference

REVIEW

There are currently no reviews for Tropomyosin 3 antibody (GTX16386). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399