GeneTex
United States (US)

Tropomyosin 3 antibody

GTX16386_20180530_ICCIF_18121410_686.jpg
GTX16386_20180530_WB_18121410_568.jpg

Cat No. GTX16386

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

33 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-284 of human TPM3 (NP_689476.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tropomyosin 3,Capm1,Cftd,Hel-189,Hel-S-82P,Nem1,Ok/Sw-Cl.5,Tm-5,Tm3,Tm30,Tm30Nm,Tm5,Tpm3Nu,Tpmsk3,Trk,Hscp30,Tpm3

Background

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16386_20180530_ICCIF_18121410_686.jpg

GTX16386 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX16386 Tropomyosin 3 antibody.
Blue : DAPI

GTX16386_20180530_WB_18121410_568.jpg

GTX16386 WB Image

WB analysis of various samples using GTX16386 Tropomyosin 3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319