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Tropomyosin 3 antibody

Anti-Tropomyosin 3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16386
Anti-Tropomyosin 3 antibody used in Western Blot (WB). GTX16386

Cat No. GTX16386

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

33 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-284 of human TPM3 (NP_689476.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

tropomyosin 3 , CAPM1 , CFTD , HEL-189 , HEL-S-82p , NEM1 , OK/SW-cl.5 , TM-5 , TM3 , TM30 , TM30nm , TM5 , TPM3nu , TPMsk3 , TRK , hscp30

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES
Anti-Tropomyosin 3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16386

GTX16386 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX16386 Tropomyosin 3 antibody.
Blue : DAPI

Anti-Tropomyosin 3 antibody used in Western Blot (WB). GTX16386

GTX16386 WB Image

WB analysis of various samples using GTX16386 Tropomyosin 3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE
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REVIEW
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Package List Price ($)
$ 319