APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1/500 - 1/2000 |
1/200 - 1/1000 |
1/200 - 1/400 |
1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of human TNNI2 expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
troponin I2, fast skeletal type , AMCD2B , DA2B , FSSV , fsTnI
Background
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
Database
Research Area
DATA IMAGES
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GTX60507 FACS Image
FACS analysis of NIH3T3 cells using GTX60507 Troponin I fast skeletal muscle antibody [2F12A11]. Blue : Troponin I fast skeletal muscle Red : negative control
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GTX60507 WB Image
WB analysis of HEK293 (1) and Troponin I fast skeletal muscle (AA: 1-182)-hIgGFc transfected HEK293 (2) cell lysate using GTX60507 Troponin I fast skeletal muscle antibody [2F12A11].
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GTX60507 ELISA Image
ELISA analysis of antigen using GTX60507 Troponin I fast skeletal muscle antibody [2F12A11].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng
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GTX60507 IHC-P Image
IHC-P analysis of rabbit cardiac muscle tissue using GTX60507 Troponin I fast skeletal muscle antibody [2F12A11].
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GTX60507 WB Image
WB analysis of human Troponin I fast skeletal muscle (AA: 1-182) recombinant protein using GTX60507 Troponin I fast skeletal muscle antibody [2F12A11].
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GTX60507 IHC-P Image
IHC-P analysis of human striated muscle tissue using GTX60507 Troponin I fast skeletal muscle antibody [2F12A11].
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GTX60507 IHC-P Image
IHC-P analysis of human cardiac muscle tissue using GTX60507 Troponin I fast skeletal muscle antibody [2F12A11].
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REFERENCE
There are currently no references for Troponin I fast skeletal muscle antibody [2F12A11] (GTX60507). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Troponin I fast skeletal muscle antibody [2F12A11] (GTX60507). Be the first to share your experience with this product.