*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Raji , THP-1 , HL-60 , TWIST1 transfected 293T lysates , human TWIST1-transfected 293T , Jurkat , *OECM1 , *CL1-5 , *Toledo , *SU-DHL-5 , *HT , *DB , *RL95-2 , *MDA-MB-231
Bovine, Chicken, Japanese Medaka, Xenopus laevis, Chimpanzee(>80% identity)
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human Twist1/2. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ACS3 antibody, B-HLH DNA binding protein antibody, BPES2 antibody, BPES3 antibody, CRS1 antibody, DERMO1 antibody, H-twist antibody, MGC117334 antibody, SCS antibody, TWIST antibody, TWIST homolog of drosophila antibody, TWIST1 antibody, TWIST2 antibody, bHLHa38 antibody, bHLHa39 antibody, class A basic helix-loop-helix protein 38 antibody, class A basic helix-loop-helix protein 39 antibody, dermis-expressed protein 1 antibody, twist homolog 2 (Drosophila) antibody, twist-related bHLH protein Dermo1 antibody, twist-related protein 1 antibody, twist-related protein 2 antibody
This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Aug 2017]