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Tyrosinase antibody [TYR/2024R]

Anti-Tyrosinase antibody [TYR/2024R] used in IHC (Paraffin sections) (IHC-P). GTX02735

Cat. No. GTX02735

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 TYR/2024R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all Tyrosinase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human full-length tyrosinase (TYR) protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tyrosinase , ATN , CMM8 , OCA1 , OCA1A , OCAIA , SHEP3

Background

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-Tyrosinase antibody [TYR/2024R] used in IHC (Paraffin sections) (IHC-P). GTX02735

GTX02735 IHC-P Image

IHC-P analysis of human melanoma tissue section using GTX02735 Tyrosinase antibody [TYR/2024R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529