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Tyrosinase antibody

Anti-Tyrosinase antibody used in Immunohistochemistry (IHC). GTX15175
Anti-Tyrosinase antibody used in Immunohistochemistry (IHC). GTX15175

Cat No. GTX15175

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P, IHC

Reactivity

Human
Package
500 μl ($289)

APPLICATION

Application Note

IHC-P: Use at a dilution of 1/100 for 10 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

60 kDa. ( Note )

Positive Control

Melanoma tissue slides

PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human)

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

tyrosinase , ATN , CMM8 , OCA1 , OCA1A , OCAIA , SHEP3

Background

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-Tyrosinase antibody used in Immunohistochemistry (IHC). GTX15175

GTX15175 IHC Image

Anti-Tyrosinase antibody used in Immunohistochemistry (IHC). GTX15175

GTX15175 IHC Image

Human melanoma stained with GTX15175

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf