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Tyrosine Hydroxylase antibody [1B5]

Anti-Tyrosine Hydroxylase antibody [1B5] used in IHC (Paraffin sections) (IHC-P). GTX01922

Cat. No. GTX01922

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1B5

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human, Mouse, Rat
Package
500 μl ($619)
See all Tyrosine Hydroxylase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:40

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Mouse

Immunogen

Prokaryotic recombinant protein corresponding to a portion of the carboxyl terminal end of the mouse tyrosine hydroxylase molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tyrosine hydroxylase , DYT14 , DYT5b , TYH

Background

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Tyrosine Hydroxylase antibody [1B5] used in IHC (Paraffin sections) (IHC-P). GTX01922

GTX01922 IHC-P Image

IHC-P analysis of human midbrain using GTX01922 Tyrosine Hydroxylase antibody [1B5]. Note cytoplasmic staining of catecholaminergic cells and their processes.

REFERENCE

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REVIEW

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Package List Price ($)
$ 619