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UACA antibody [AE-5]

Anti-UACA antibody [AE-5] used in Western Blot (WB). GTX35155

Cat. No. GTX35155

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AE-5

Isotype

 IgG1

Application

 WB, ICC/IF, FACS

Reactivity

 Human, Mouse
Package
100 μg ($529)
See all UACA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
ICC/IF 1-2μg/ml
FACS 1-2μg/10⁶ cells
Not tested in other applications.

Calculated MW

162 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Nuclei of myeloid leukemia biopsy cells

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NUCLING , UACA , uveal autoantigen with coiledcoil domains and ankyrin repeats , uveal autoantigen with coiled-coil domains and ankyrin repeats

Cellular Localization

Nucleus,Cytoplasm,Cytoskeleton

Background

This gene encodes a protein that contains ankyrin repeats and coiled coil domains and likely plays a role in apoptosis. Studies in rodents have implicated the encoded protein in the stimulation of apoptosis and the regulation of mammary gland involution, in which the mammary gland returns to its pre-pregnant state. This protein has also been proposed to negatively regulate apoptosis based on experiments in human cell lines in which the protein was shown to interact with PRKC apoptosis WT1 regulator protein, also known as PAR-4, and inhibit translocation of the PAR-4 receptor. Autoantibodies to this protein have been identified in human patients with panuveitis and Graves' disease. Differential expression of this gene has been observed in various human cancers. [provided by RefSeq, May 2017]

Database

Research Area

DATA IMAGES

Anti-UACA antibody [AE-5] used in Western Blot (WB). GTX35155

GTX35155 WB Image

WB analysis of A549 cell lysate using GTX35155 UACA antibody [AE-5].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529