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UGDH antibody

Anti-UGDH antibody used in IHC (Paraffin sections) (IHC-P). GTX32948
Anti-UGDH antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32948
Anti-UGDH antibody used in Western Blot (WB). GTX32948
Anti-UGDH antibody used in IHC (Paraffin sections) (IHC-P). GTX32948

Cat No. GTX32948

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_003350.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

UDP-glucose 6-dehydrogenase , GDH , UDP-GlcDH , UDPGDH , UGD

Background

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

DATA IMAGES

Anti-UGDH antibody used in IHC (Paraffin sections) (IHC-P). GTX32948

GTX32948 IHC-P Image

IHC-P analysis of rat brain tissue using GTX32948 UGDH antibody.
Dilution : 1:100

Anti-UGDH antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32948

GTX32948 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX32948 UGDH antibody.
Blue : DAPI

Anti-UGDH antibody used in Western Blot (WB). GTX32948

GTX32948 WB Image

WB analysis of various samples using GTX32948 UGDH antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-UGDH antibody used in IHC (Paraffin sections) (IHC-P). GTX32948

GTX32948 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX32948 UGDH antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 329