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UGT1A antibody

Anti-UGT1A antibody used in Western Blot (WB). GTX114131
Anti-UGT1A antibody used in Western Blot (WB). GTX114131
Anti-UGT1A antibody used in Western Blot (WB). GTX114131

Cat No. GTX114131

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:5000-1:20000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Positive Control

Human liver , Mouse liver , Rat liver

Predict Reactivity

Sheep, Bovine, Cat, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris-Glycine (pH7), 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.93 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human UGT1A. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11179114

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

BILIQTL1 antibody , GNT1 antibody , HUG-BR1 antibody , UDPGT antibody , UDPGT 1-1 antibody , UGT1 antibody , UGT1A antibody , UGT1A1 antibody , UDP-glucuronosyltransferase 1A1 antibody , UDP glycosyltransferase 1 family , polypeptide A1 antibody , bilirubin-specific UDPGT isozyme 1 antibody , UGT1.1 antibody , UDP-glucuronosyltransferase 1-1 antibody , UGT-1A antibody , bilirubin UDP-glucuronosyltransferase isozyme 1 antibody , UGT1*1 antibody , bilirubin UDP-glucuronosyltransferase 1-1 antibody , UDP-glucuronosyltransferase 1-A antibody , UGT1-01 antibody , UDP glucuronosyltransferase 1 family , polypeptide A1 antibody

Cellular Localization

Microsome , Endoplasmic reticulum membrane; Single-pass membrane protein

Background

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq]

Research Area

DATA IMAGES

Anti-UGT1A antibody used in Western Blot (WB). GTX114131

GTX114131 WB Image

Human tissue extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with UGT1A antibody (GTX114131) diluted at 1:10000.

Anti-UGT1A antibody used in Western Blot (WB). GTX114131

GTX114131 WB Image

UGT1A antibody detects UGT1A protein by Western blot analysis.
A. 50 μg mouse liver lysate/extract
7.5 % SDS-PAGE
UGT1A antibody (GTX114131) dilution: 1:10000

Anti-UGT1A antibody used in Western Blot (WB). GTX114131

GTX114131 WB Image

UGT1A antibody detects UGT1A protein by Western blot analysis.
A. 50 μg rat liver lysate/extract
7.5 % SDS-PAGE
UGT1A antibody (GTX114131) dilution: 1:5000

REFERENCE

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 329
$ 169