GeneTex
United States (US)

UGT1A4 antibody

GTX32949_20180530_WB_18121410_363.jpg
GTX32949_20180530_IHC-P_18121410_744.jpg

Cat No. GTX32949

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

60 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 29-150 of human UGT1A4 (NP_009051.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Udp Glucuronosyltransferase Family 1 Member A4,Hug-Br2,Udpgt,Udpgt 1-4,Ugt-1D,Ugt1-04,Ugt1.4,Ugt1A4S,Ugt1D,Ugt1A4

Background

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX32949_20180530_WB_18121410_363.jpg

GTX32949 WB Image

WB analysis of various samples using GTX32949 UGT1A4 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX32949_20180530_IHC-P_18121410_744.jpg

GTX32949 IHC-P Image

IHC-P analysis of human kidney cancer tissue using GTX32949 UGT1A4 antibody.
Dilution : 1:200

Package List Price ($)
$ 329