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UGT1A6 antibody

Anti-UGT1A6 antibody used in IHC (Paraffin sections) (IHC-P). GTX113980
Anti-UGT1A6 antibody used in Western Blot (WB). GTX113980
Anti-UGT1A6 antibody used in Western Blot (WB). GTX113980
Anti-UGT1A6 antibody used in Western Blot (WB). GTX113980

Cat. No. GTX113980

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all UGT1A6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

Positive Control

mouse liver , A431 , H1299 , 293T , A431 , HeLa , HepG2

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.56 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human UGT1A6. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2038209

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

UDP glucuronosyltransferase family 1 member A6 , GNT1 , HLUGP , HLUGP1 , UDPGT , UDPGT 1-6 , UGT-1A , UGT-1C , UGT-1E , UGT1 , UGT1-01 , UGT1-03 , UGT1-05 , UGT1.1 , UGT1.3 , UGT1.5 , UGT1A , UGT1A1 , UGT1A3 , UGT1A5 , UGT1A6S , UGT1C , UGT1E , UGT1F , hUG-BR1

Cellular Localization

Microsome , Endoplasmic reticulum membrane; Single-pass membrane protein

Background

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-UGT1A6 antibody used in IHC (Paraffin sections) (IHC-P). GTX113980

GTX113980 IHC-P Image

Immunohistochemical analysis of paraffin-embedded OV90 xenograft, using UGT1A6(GTX113980) antibody at 1:100 dilution.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-UGT1A6 antibody used in Western Blot (WB). GTX113980

GTX113980 WB Image

Sample (30 ug of whole cell lysate)
A: A431 (GTX27909)
B: H1299
7.5% SDS PAGE
GTX113980 diluted at 1:1000

Anti-UGT1A6 antibody used in Western Blot (WB). GTX113980

GTX113980 WB Image

UGT1A6 antibody detects UGT1A6 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with UGT1A6 antibody (GTX113980) diluted by 1:1000.

Anti-UGT1A6 antibody used in Western Blot (WB). GTX113980

GTX113980 WB Image

UGT1A6 antibody detects UGT1A6 protein by Western blot analysis.
A. 50 μg mouse liver lysate/extract
7.5 % SDS-PAGE
UGT1A6 antibody (GTX113980) dilution: 1:500

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169