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UGT1A7 antibody, N-term

Anti-UGT1A7 antibody, N-term used in Western Blot (WB). GTX46071
Anti-UGT1A7 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46071

Cat. No. GTX46071

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
50 μg ($399)
See all UGT1A7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Positive Control

human B lymphoblast

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human UGT1A7

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

UDP glucuronosyltransferase family 1 member A7 , GNT1 , UDPGT , UDPGT 1-7 , UGT-1A , UGT-1G , UGT1 , UGT1-01 , UGT1-07 , UGT1.1 , UGT1.7 , UGT1A , UGT1A1 , UGT1G , hUG-BR1

Cellular Localization

Microsome,Endoplasmic reticulum membrane

Background

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-UGT1A7 antibody, N-term used in Western Blot (WB). GTX46071

GTX46071 WB Image

WB analysis of human B lymphoblast cells using GTX46071 UGT1A7 antibody at 0.2-1μg/ml.

Anti-UGT1A7 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46071

GTX46071 IHC-P Image

IHC-P analysis of human liver tissue using GTX46071 UGT1A7 antibody at 1:100. Left to right : DAPI, UGT1A7, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer was performed.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399